CENTOGENE’s Medical Genetic Liaison Kriti Menon will provide an overview of WGS, literature-based evidence, its advantages & limitations, and the relevance of research variants & data re-evaluation. At the end of the webinar, she will share different clinical cases studies and lessons learned.
Until now, a common industry approach for testing HLA-A 31:01 (tag SNP rs1061235) has produced a high false positive rate of approximately 40%. Without separate verification, this could have the clinical outcome of inappropriately excluding the use of a valuable drug, carbamazepine which is associated with a 5-fold increased incidence in hypersensitivity reactions in the presence of this allele.
Mark your calendars for 13 January (Wednesday) for our next case study webinar, ‘The Role of CNVs in Increasing the Diagnostic Yield of WES.’
MORE women with breast cancer could be spared chemotherapy if doctors switched to a new genetic test, research shows.
“EPclin (EndoPredict) Markedly Outperformed RS (Oncotype DX®) Across the 10-Year Follow-up Period” in a Large Head-to-Head Breast Cancer Study