Because Patients Matter
Make Better-Informed Decisions
Be Ready Against Hereditary Cancer
Helping Children Lead Better Lives

Reproductive Health and Prenatal Genetic Testing

Throughout the CentoTalk, Clarice Loh provides a detailed overview of Read More

Four Benefits of Genetic Testing

We understand there is a lot of misinformation and confusion Read More

myChoice HRD: The optimal approach to the select patient with OC who can benefit from a PARPi treatment.

Mutations in BRCA1 and BRCA2 genes are the main cause Read More

Centogene: Prenatal Genetic Testing Beyond NIPT

Major fetal structural anomalies occur in approximately 2 – 4% Read More

Case Study Series: Whole Genome Sequencing – A First Tier and Comprehensive Genetic Test

CENTOGENE’s Medical Genetic Liaison Kriti Menon will provide an overview of WGS, literature-based evidence, its advantages & limitations, and the relevance of research variants & data re-evaluation. At the end of the webinar, she will share different clinical cases studies and lessons learned.

Cancer is a disease of abnormal gene function. Some gene changes that lead to cancer may be inherited. Breast, ovarian, prostate, and colon are some of these cancers that are linked to a family history. The genetic mutations that cause many of the known hereditary cancer syndromes have been identified, and genetic testing can confirm whether a condition is the result of an inherited syndrome. Genetic profiling may help you or other family members in planning health care for the future.

A companion diagnostic is a medical device which provides information that is essential for the safe and effective use of a corresponding drug. The test helps health care professionals identify patients who are most likely to benefit from a particular therapeutic product and patients who are likely to be at increased risk for serious side effects as a result of treatment. Companion diagnostics can also be used to monitor patient response to treatment for the purpose of adjusting treatment to achieve improved safety or effectiveness.

Rare genetic disorders can go undiagnosed for years. The lack of a diagnosis can have considerable adverse effects for patients and their families, including failure to identify potential treatments, failure to recognize risk of recurrence in subsequent pregnancies, and failure to provide anticipatory guidance and prognosis. Genetic testing has proven to be effective in detecting rare variants in an individual’s genome, offering hope to individuals with previously undiagnosed or untreated rare disorders.

Nearly 1 in 5 individuals suffer from mental illness. There are over 270 medications containing warnings, precautions and dosage recommendations based on specific gene variants. Two-thirds of patients will not achieve complete relief from their first medication.* Emerging science has allowed clinicians to use genetic tests to assist in the safe and appropriate selection of pharmacologic treatment for individuals suffering from mental illness, by unlocking unique insights to quickly identify a personalized treatment plan to help avoid the painful process of treatment by trial and error. *Based on the STAR*D Trial

Radiotherapy is a treatment where ionizing radiation is used to kill cancer cells and shrink tumours by damaging their DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or dies, and they are broken down and removed by the body. Radiotherapy uses low energy ionizing radiation that avoids deep tissue damage an minimises scarring. This makes it superior in treating superficial tumours, and an excellent alternative to surgery for skin cancer in sensitive locations, such as the folds of the nose, eyelids or ears.

Predictive, Preventive, and Personalized Medicine

Predictive, Preventive, and Personalized Medicine (PPPM) is the new integrative concept in healthcare that enables to predict individual predisposition before onset of the disease, to provide targeted preventive measures and create personalized treatment algorithms tailored to the person. PPPM offers great promise for the future practice of medicine resulting in substantial improvement of the quality of life.

Reproductive Health and Prenatal Genetic Testing

Four Benefits of Genetic Testing

myChoice HRD: The optimal approach to the select patient with OC who can benefit from a PARPi treatment.

Centogene: Prenatal Genetic Testing Beyond NIPT

Case Study Series: Whole Genome Sequencing – A First Tier and Comprehensive Genetic Test

Cancer

Companion Diagnostics

Unknown Genetic Disorders

Psychiatric Disorders

Predictive, Preventive, and Personalized Medicine