Because Patients Matter
Make Better-Informed Decisions
Be Ready Against Hereditary Cancer
Helping Children Lead Better Lives
Mutations in BRCA1 and BRCA2 genes are the main cause Read More
CENTOGENE’s Medical Genetic Liaison Kriti Menon will provide an overview of WGS, literature-based evidence, its advantages & limitations, and the relevance of research variants & data re-evaluation. At the end of the webinar, she will share different clinical cases studies and lessons learned.
Cancer is a disease of abnormal gene function. Some gene changes that lead to cancer may be inherited. Breast, ovarian, prostate, and colon are some of these cancers that are linked to a family history. The genetic mutations that cause many of the known hereditary cancer syndromes have been identified, and genetic testing can confirm whether a condition is the result of an inherited syndrome. Genetic profiling may help you or other family members in planning health care for the future.
A companion diagnostic is a medical device which provides information that is essential for the safe and effective use of a corresponding drug. The test helps health care professionals identify patients who are most likely to benefit from a particular therapeutic product and patients who are likely to be at increased risk for serious side effects as a result of treatment. Companion diagnostics can also be used to monitor patient response to treatment for the purpose of adjusting treatment to achieve improved safety or effectiveness.
Rare genetic disorders can go undiagnosed for years. The lack of a diagnosis can have considerable adverse effects for patients and their families, including failure to identify potential treatments, failure to recognize risk of recurrence in subsequent pregnancies, and failure to provide anticipatory guidance and prognosis. Genetic testing has proven to be effective in detecting rare variants in an individual’s genome, offering hope to individuals with previously undiagnosed or untreated rare disorders.
Nearly 1 in 5 individuals suffer from mental illness. There are over 270 medications containing warnings, precautions and dosage recommendations based on specific gene variants. Two-thirds of patients will not achieve complete relief from their first medication.* Emerging science has allowed clinicians to use genetic tests to assist in the safe and appropriate selection of pharmacologic treatment for individuals suffering from mental illness, by unlocking unique insights to quickly identify a personalized treatment plan to help avoid the painful process of treatment by trial and error. *Based on the STAR*D Trial
Radiotherapy is a treatment where ionizing radiation is used to kill cancer cells and shrink tumours by damaging their DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or dies, and they are broken down and removed by the body. Radiotherapy uses low energy ionizing radiation that avoids deep tissue damage an minimises scarring. This makes it superior in treating superficial tumours, and an excellent alternative to surgery for skin cancer in sensitive locations, such as the folds of the nose, eyelids or ears.