Personalized Medicine For You

Cancer

Cancer is a disease of abnormal gene function. Some gene changes that lead to cancer may be inherited. Breast, ovarian, prostate, and colon are some of these cancers that are linked to a family history. The genetic mutations that cause many of the known hereditary cancer syndromes have been identified, and genetic testing can confirm whether a condition is the result of an inherited syndrome. Genetic profiling may help you or other family members in planning health care for the future.

Hereditary Cancer Syndrome

myRisk™ – Myriad’s myRisk™ is a test developed by Myriad Genetic Laboratories that measures an individual’s risk of developing hereditary cancer syndromes.

Breast Cancer

Hereditary Breast and Ovarian Cancer
BRACAnalysis® – Myriad’s BRACAnalysis® test assesses a person’s risk of developing hereditary breast or ovarian cancer based on the detection of mutations in the BRCA1 and BRCA2 genes.

Necessity of Chemotherapy
EndoPredict® – Myriad’s EndoPredict® is a prognostic 2nd generation IVD gene expression test to determine the risk of distant metastases in patients with estrogen receptor positive, HER2-negative primary breast cancer.

Colorectal Cancer

Lynch Syndrome
COLARIS® – Myriad’s COLARIS® testing assesses a person’s risk of developing hereditary colorectal cancer and a woman’s risk of developing hereditary uterine/endometrial cancer by detecting disease-causing mutations in the MLH1, MSH2, MSH6 and PMS2 genes.

Polyposis Syndrome
COLARIS AP® – Myriad’s COLARIS AP® testing assesses a person’s risk of developing hereditary colorectal polyps and cancer by detecting mutations in the APC and MYH genes.

Prostate Cancer

Prolaris® – Myriad’s Prolaris® is a test that measures how fast the cells in your tumor are dividing. Since you have had a biopsy, that tissue sample can be used to determine your Prolaris Score.

Skin Cancer

Melaris® – Myriad’s Melaris® is a test developed by Myriad Genetic Laboratories that measures a person’s risk of developing hereditary melanoma.

Pancreatic Cancer

PANEXIA™ – Myriad’s PANEXIA™ is a genetic test specifically created to detect mutations in genes that result in an increased risk of pancreatic cancer, offering insight about the risk of future hereditary cancers for patients and their families.

Psychiatric Disorders

Nearly 1 in 5 individuals suffer from mental illness. There are over 270 medications containing warnings, precautions and dosage recommendations based on specific gene variants.  Two thirds of patients will not achieve complete relief from their first medication.*  Emerging science has allowed Genomind to develop a test designed to assist in the safe and appropriate selection of pharmacologic treatment for individuals who suffer from mental illness. Genomind’s leading mental health genetic test was designed to unlock unique insights for your clinician to more quickly identify a personalized treatment plan to help you avoid the painful process of treatment by trial and error

*Depression Patients, Based on the STAR*D Trial

Mental Illness and Brain Disorders

Genomind Professional PGx Express is a pharmacogenetic test  designed to assist in the safe and appropriate selection of pharmacologic treatment for individuals who suffer from mental illness. The test offers guidance to help minimize the trial and error process of finding a safe and effective medication at the appropriate dose.

The test identifies patient-specific genetic markers that affect how patients may react to medications and other treatments. It is an easily administered cheek swab test that analyzes up to 24 key genes. These genes were selected based on FDA prescribing information, consensus expert guidelines, and data derived from hundreds of studies showing that variations in these genes may inform treatment decisions.

Unknown Genetic Disorders

Rare genetic disorders can go undiagnosed for years. The lack of a diagnosis can have considerable adverse effects for patients and their families, including failure to identify potential treatments, failure to recognize risk of recurrence in subsequent pregnancies, and failure to provide anticipatory guidance and prognosis. Genetic testing has proven to be effective in detecting rare variants in an individual’s genome, offering hope to individuals with previously undiagnosed or untreated rare disorders.

Whole Genome Sequencing

Whole genome sequencing identifies almost all changes in a patient’s DNA by sequencing both the entire coding and non-coding regions of the genome. CentoGenome® – our whole genome sequencing service – is the most complete solution to diagnose genetically complex and undiagnosed cases with the highest level of certainty.

Whole Exome Sequencing

Clinical Exome Sequencing is a test for identifying disease causing DNA mutations in the protein coding (exon) regions of the human genome. Along with the patient’s clinical presentation and other known disease markers, CentoXome® provides a powerful means by which genetic disorders can be uncovered in an individual – leading to more informed approaches for personalized care and treatment.

Radiotherapy

Radiotherapy is a treatment where ionizing radiation is used to kill cancer cells and shrink tumours by damaging their DNA. Cancer cells whose DNA is damaged beyond repair stop dividing or dies, and they are broken down and removed by the body.

Radiotherapy uses low energy ionizing radiation that avoids deep tissue damage and minimises scarring. This makes it superior in treating superficial tumours, and an excellent alternative to surgery for skin cancer in sensitive locations, such as the folds of the nose, eyelids or ears.

Enteric Disease

Enteric diseases are intestinal illness caused by micro-organismssuch as viruses, bacteria and parasites. These diseases are most frequently acquired through contaminated food and water. Although enteric micro-organisms typically enter the body through the mouth, some can spread from person to person. Every year, millions of cases of foodborne illness occur in the United States, and the illness burden is even higher in developing countries. Much of this burden could be prevented with better science and prevention tools.