Skin cancer is one of the most common forms of cancer. Melanoma is the most serious form of this cancer and, even though it accounts for less than five percent of all skin cancers, it is responsible for the majority of skin cancer deaths. The cancerous growths develop when unrepaired DNA damage to skin cells – most often caused by ultraviolet radiation from the sun or tanning beds – triggers mutations that cause skin cells to multiply rapidly and form malignant tumors. Melanomas often resemble moles and some of them actually develop from moles. The majority of melanomas are black or brown, but they can also be skin-colored, pink, red, purple, blue or white. If melanoma is caught and treated early, it is almost always curable. However, if it is not, the cancer can advance and spread to other parts of the body, where it becomes hard to treat and can even be fatal.
Hereditary melanoma is an inherited condition. Several genes have been associated with hereditary melanoma, including the p16 gene (also called CDKN2A or INK4A).
What is myPath® Melanoma?
myPath® Melanoma is a 23-gene expression signature test, developed by Myriad Genetic Laboratories as an objective and accurate method for differentiating malignant melanoma from benign nevi that overcomes some of these limitations.
Is myPath® Melanoma suitable for me?
myPath® Melanoma is for individuals at risk for hereditary melanoma. If you and your doctor determine that you may be at risk for hereditary melanoma, myPath® Melanoma is right for you.
Myriad Genetics’ Hereditary Cancer Quiz helps you to assess whether you might be a good candidate for testing. This quiz can help you get the information you need to discuss your risk of cancer with your healthcare provider and ask for further evaluation. If you take the quiz and find red flags in your own history or your family history, you may benefit from hereditary cancer testing.
The quiz will help you determine if you are at risk for the following hereditary cancers:
- Breast Cancer
- Ovarian Cancer
- Colon Cancer
- Uterine Cancer
- Pancreatic Cancer
To begin the process of seeing if genetic testing is right for you, check out Myriad’s Hereditary Cancer Quiz: https://www.hereditarycancerquiz.com/
How will myPath® Melanoma testing benefit me?
Knowing if you have a gene mutation can help you know your risk of hereditary cancer and inform your family of their potential risk of hereditary cancer.
The myPath® Melanoma test results may enable you and your family to make more informed choices and help you to be ready against hereditary cancer. They can also help your doctor manage your healthcare needs more effectively.
What is the unique advantage of Myriad myPath® Melanoma testing?
No company has more experience in genetic testing for hereditary cancer than Myriad.
Over the last 20 years, Myriad has delivered more than one million test results.
Myriad has the lowest Variant of Uncertain Significance (VUS) rate globally with a <3% VUS rate (0.6% for BRCA1 mutations). A lower VUS rate means a lower chance of getting an uncertain result, which means more confidence and clarity in your results.
myPath® Melanoma FAQs
How do I get tested?
Speak to your doctor. Once your doctor orders a test for you from us, we will take care of the rest. The clinic will take a small blood sample and send it to the lab for testing. The lab cannot accept a test directly from you, as a doctor first needs to assess whether or not the test is right for you. Once the testing is completed, a report will be sent to your doctor who will then go through and explain your results to you, and suggest the next steps.
Can I use any other sample collection kit that is not provided by Myriad?
No! Our processes have been optimized and validated with the kits we provide.
Which completed forms must accompany my sample?
The clinic will help you complete and sign an Informed Consent Form. This form will be submitted with the sample. The consent form will be used to match your sample to the test request submitted by the doctor, and is needed to let the lab know that you have agreed to send your sample for the test. Samples received without these forms cannot be processed, as your consent is required to test your sample.
Who will receive the test results?
Myriad will provide your test report to the healthcare professional who ordered the test.
Why are the results of testing sent directly to the ordering healthcare professional rather than the patient or parent of a patient?
Results are sent to the ordering healthcare professional as they would need to discuss the results, result interpretation, treatment management, and any follow-up testing with you.