Hereditary Cancer Syndrome

Hereditary Cancer Syndrome includes Hereditary Breast and Ovarian Cancer (HBOC), Hereditary Colon and Gynecologic Cancer, Hereditary Melanoma and Hereditary Pancreatic Cancer. These gene mutations can be inherited from either your mother or father, and the inherited condition may cause an increased risk for these cancers.

Am I at risk for hereditary cancer?

This quiz can help you get the information you need to discuss your risk of hereditary cancer syndrome with your doctor, and ask for further evaluation. If you take the quiz and find red flags in your own history or your family history, you may benefit from hereditary cancer testing. This quiz covers the following hereditary cancers:

  • Breast Cancer
  • Ovarian Cancer
  • Colon Cancer
  • Uterine Cancer
  • Pancreatic Cancer

To begin the process of seeing if genetic testing is right for you, check out Myriad’s Hereditary Cancer Quiz:

What is myRisk™?

myRisk™ is a test developed by Myriad Genetic Laboratories that measures an individual’s risk of developing hereditary cancer syndromes. It does not tell you whether you have cancer, but detects mutations in various genes. These are the gene mutations that are responsible for the majority of eight hereditary cancers. Only a small blood sample is taken for analysis.

How will myRisk™ testing benefit me?

Knowing if you have a gene mutation among the 35 gene panel can help you know your risk of hereditary cancer and inform your family of their potential risk of hereditary cancer. The Myriad myRisk™ test results may enable you and your family to make more informed choices and help you to be ready against hereditary cancer.

Patients already diagnosed with cancer can also benefit from knowing if their cancer may be a result of such mutations, as the information can help doctors better manage the patient’s treatment and healthcare needs.

What is the unique advantage of Myriad myRisk™ testing?

No company has more experience in genetic testing for hereditary cancer than Myriad.

Over the last 20 years, Myriad has delivered more than one million test results.

Myriad has the lowest Variant of Uncertain Significance (VUS) rate globally with a <3% VUS rate (0.6% for BRCA1 mutations). A lower VUS rate means a lower chance of getting an uncertain result, which means more confidence and clarity in your results.


myRisk™ FAQs

I already know I have a family history of cancer. Why should I get tested?

Testing for a hereditary cancer risk helps you and your healthcare professional understand your risk so you can make the best choices for preventive care. Knowing your family history is an important first step, but testing can give you a more accurate picture of your risk.

I already have cancer. Why should I get tested?

Testing for a hereditary cancer helps you and your healthcare professional understand your risk for developing a second primary cancer. This information can allow you to make the best choices for preventive care.

Is testing recommended for everyone?

While testing is the most accurate way to determine the risk of hereditary cancer, only people who have cancer in their family or a personal history of the disease need to be tested. If you have had cancer and/or cancer runs in your family, let your healthcare professional know. To help you assess whether you may benefit from hereditary cancer genetic testing, take the Myriad Hereditary Cancer Quiz. This simple, 30-second quiz can help you get the information you need to discuss your risk of cancer with your healthcare professional and ask for further evaluation.

How do I get tested?

Speak to your doctor. Once your doctor orders a test for you from us, we will take care of the rest. The clinic will take a small blood sample and send it to the lab for testing. The lab cannot accept a test directly from you, as a doctor first needs to assess whether or not the test is right for you. Once the testing is completed, a report will be sent to your doctor who will then go through and explain your results to you, and suggest the next steps.

Can I use any other sample collection kit that is not provided by Myriad?

No! Our processes have been optimized and validated with the kits we provide.

Which completed forms must accompany my sample?

The clinic will help you complete and sign an Informed Consent Form. This form will be submitted with the sample. The consent form will be used to match your sample to the test request submitted by the doctor, and is needed to let the lab know that you have agreed to send your sample for the test. Samples received without these forms cannot be processed, as your consent is required to test your sample.

Who will receive the test results?

Myriad will provide your test report to the healthcare professional who ordered the test.

Why are the results of testing sent directly to the ordering healthcare professional rather than the patient or parent of a patient?

Results are sent to the ordering healthcare professional as they would need to discuss the results, result interpretation, treatment management, and any follow-up testing with you.